The microbial sequencing effort at The Genome Institute currently includes organisms in several categories. One major effort involves the human microbiome - the collection of microbes that colonize the human body. The Genome Institute is applying next generation sequencing and analysis technology to analyze the genomes of these and other microbes, characterize the communities they form and measure how they change in health and disease.
These projects involve sequencing a variety of prokaryotes, such as human intestinal and enteric bacteria, bioluminescent bacteria, human microbiome reference genomes and many others.
The Genome Institute is working to sequence key viruses found in the human microbiome of healthy and diseased individuals. These include viruses such as the herpes, hepatitis and human papilloma viruses.
The Genome Institute is sequencing eukaryotic microorganisms that include various types of fungi (yeasts, molds, etc.) and other single-celled organisms known as protists.