Tina Graves-Lindsay
Research Accomplishments & Interests
Tina Graves-Lindsay, M.S., joined The Genome Institute in 1996 and is currently the leader of the Reference Genomes group. This group is responsible for improving the human and mouse reference sequences by correcting any misrepresented regions and closing as many remaining gaps as possible. This effort is also producing alternate assemblies of structurally variant loci for the human genome. Along with her duties in the Reference Genome group, she also oversees the Clone-Based Library Core and Sorting groups.
Other Biographical Information
Tina received her Bachelor of Science degree from Southwest Missouri State University and her Master’s Degree in Microbiology from Southern Illinois University at Carbondale.
Selected Publications
Dennis MY, Nuttle X, Sudmant PH, Antonacci F, Graves TA, Nefedov M, Rosenfeld JA, Sajjadian…
Evolution of Human-Specific Neural SRGAP2 Genes by Incomplete Segmental Duplication.
Cell. 2012 May 2. [Epub ahead of print] PubMed | View Abstract
Itsara A, Vissers LE, Steinberg KM, Meyer KJ, Zody MC, Koolen DA, de Ligt J,…
Resolving the breakpoints of the 17q21.31 microdeletion syndrome with next-generation sequencing.
Am J Hum Genet. 2012 Apr 6;90(4):599-613. PubMed | View Abstract
Ventura M, Catacchio C, Sajjadian S, Vives L, Sudmant P, Marques-Bonet T, Graves TA, Wilson…
The evolution of African great ape subtelomeric heterochromatin and the fusion of human chromosome 2
Genome Res. 2012 Mar 14. [Epub ahead of print] PubMed | View Abstract
Scally A, Dutheil JY, Hillier LW, Jordan GE, Goodhead I, Herrero J, Hobolth A, Lappalainen…
Insights into hominid evolution from the gorilla genome sequence.
Nature. 2012 Mar 7;483(7388):169-75. doi: 10.1038/nature10842. PubMed | View Abstract
Hughes JF, Skaletsky H, Brown LG, Pyntikova T, Graves T, Fulton RS, Dugan S, Ding…
Strict evolutionary conservation followed rapid gene loss on human and rhesus Y chromosomes.
Nature. 2012 Feb 22. doi: 10.1038/nature10843. [Epub ahead of print] PubMed | View Abstract
Lindblad-Toh K, Garber M, Zuk O, Lin MF, Parker BJ, Washietl S, Kheradpour P, Ernst…
A high-resolution map of human evolutionary constraint using 29 mammals.
Nature. 2011 Oct 12;478(7370):476-82. doi: 10.1038/nature10530. PubMed | View Abstract
Church DM, Schneider VA, Graves T, Auger K, Cunningham F, Bouk N, Chen HC, Agarwala…
Modernizing reference genome assemblies.
PLoS Biol. 2011 Jul;9(7):e1001091. Epub 2011 Jul 5. PubMed | View Abstract
Ventura M, Catacchio CR, Alkan C, Marques-Bonet T, Sajjadian S, Graves TA, Hormozdiari F, Navarro…
Gorilla genome structural variation reveals evolutionary parallelisms with chimpanzee.
Genome Res. 2011 Jul 20. [Epub ahead of print] PubMed | View Abstract
Locke DP, Hillier LW, Warren WC, Worley KC, Nazareth LV, Muzny DM, Yang SP, Wang…
Comparative and demographic analysis of orang-utan genomes
Nature. 2011 Jan 27;469(7331):529-33. PubMed | View Abstract
Kidd JM, Graves T, Newman TL, Fulton R, Hayden HS, Malig M, Kallicki J, Kaul…
A human genome structural variation sequencing resource reveals insights into mutational mechanisms.
Cell. 2010 Nov 24;143(5):837-47. PubMed | View Abstract
Antonacci F, Kidd JM, Marques-Bonet T, Teague B, Ventura M, Girirajan S, Alkan C, Campbell…
A large and complex structural polymorphism at 16p12.1 underlies microdeletion disease risk.
Nat Genet. 2010 Sep;42(9):745-50. Epub 2010 Aug 22. PubMed | View Abstract
Bellott DW, Skaletsky H, Pyntikova T, Mardis ER, Graves T, Kremitzki C, Brown LG, Rozen…
Convergent evolution of chicken Z and human X chromosomes by expansion and gene acquisition.
Nature. 2010 Jul 11. [Epub ahead of print] PubMed | View Abstract
Kidd JM, Sampas N, Antonacci F, Graves T, Fulton R, Hayden HS, Alkan C, Malig…
Characterization of missing human genome sequences and copy-number polymorphic insertions.
Nat Methods. 2010 May;7(5):365-71. PubMed | View Abstract
Hellsten U, Harland RM, Gilchrist MJ, Hendrix D, Jurka J, Kapitonov V, Ovcharenko I, Putnam…
The genome of the Western clawed frog Xenopus tropicalis.
Science. 2010 Apr 30;328(5978):633-6. PubMed | View Abstract
Warren WC, Clayton DF, Ellegren H, Arnold AP, Hillier LW, Künstner A, Searle S, White…
The genome of a songbird.
Nature. 2010 Apr 1;464(7289):757-62. PubMed | View Abstract
