Joshua McMichael,  McDonnell Genome Institute

Publications

title citation publication date
CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer Nat Genet. 2017 Jan 31;49(2):170-174. doi: 10.1038/ng.3774. 2017-01-31
Visualizing tumor evolution with the fishplot package for R BMC Genomics. 2016 Nov 7;17(1):880 1970-08-22
DoCM: a database of curated mutations in cancer. Nat Methods. 2016 Sep 29;13(10):806-7. doi: 10.1038/nmeth.4000. 1970-08-22
CIViC: A knowledgebase for expert-crowdsourcing the clinical interpretation of variants in cancer doi: http://dx.doi.org/10.1101/072892
Patterns and functional implications of rare germline variants across 12 cancer types. Nat Commun. 2015 Dec 22;6:10086. doi: 10.1038/ncomms10086. 2015-12-15
Systematic discovery of complex insertions and deletions in human cancers. Nat Med. 2015 Dec 14. doi: 10.1038/nm.4002. [Epub ahead of print] 2015-12-14
Optimizing cancer genome sequencing and analysis. Cell Syst. 2015 Sep 23;1(3):210-223. 2015-09-23
DGIdb 2.0: mining clinically relevant drug-gene interactions. Nucleic Acids Res. 2015 Nov 3. pii: gkv1165. [Epub ahead of print] 2015-11-03
Genome Modeling System: A Knowledge Management Platform for Genomics. PLoS Comput Biol. 2015 Jul 9;11(7):e1004274. doi: 10.1371/journal.pcbi.1004274. eCollection 2015. 2015-07-09
Clonal architectures and driver mutations in metastatic melanomas. PLoS One. 2014 Nov 13;9(11):e111153. doi: 10.1371/journal.pone.0111153. eCollection 2014. 2014-11-13
Age-related mutations associated with clonal hematopoietic expansion and malignancies. Nat Med. 2014 Oct 19. doi: 10.1038/nm.3733. [Epub ahead of print] 2014-10-19
Organizing knowledge to enable personalization of medicine in cancer. Genome Biol. 2014 Aug 27;15(8):438. [Epub ahead of print] 2014-08-27
Expanding the computational toolbox for mining cancer genomes. Nat Rev Genet. 2014 Aug;15(8):556-70. doi: 10.1038/nrg3767. Epub 2014 Jul 8. 2014-08-01
Integrated analysis of germline and somatic variants in ovarian cancer. Nat Commun. 2014 Jan 22;5:3156. doi: 10.1038/ncomms4156. 2014-01-22
Mutational landscape and significance across 12 major cancer types. Nature. 2013 Oct 17;502(7471):333-9. doi: 10.1038/nature12634. 2013-10-17
DGIdb: mining the druggable genome. Nat Methods. 2013 Oct 13. doi: 10.1038/nmeth.2689. [Epub ahead of print] 2013-10-13
The Cancer Genome Atlas Pan-Cancer analysis project. Nat Genet. 2013 Sep 26;45(10):1113-20. doi: 10.1038/ng.2764. 2013-09-26
Endocrine-Therapy-Resistant ESR1 Variants Revealed by Genomic Characterization of Breast-Cancer-Derived Xenografts. Cell Rep. 2013 Sep 18. pii: S2211-1247(13)00463-4. doi: 10.1016/j.celrep.2013.08.022. [Epub ahead of print] 2013-09-18
Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia. N Engl J Med. 2013 May 1. [Epub ahead of print] 2013-05-01
Comprehensive molecular portraits of human breast tumours. Nature. 2012 Sep 23. doi: 10.1038/nature11412. [Epub ahead of print] 2012-09-23
Whole-genome analysis informs breast cancer response to aromatase inhibition. Nature. 2012 Jun 10;486(7403):353-60. doi: 10.1038/nature11143. 2012-06-10
The origin and evolution of mutations in acute myeloid leukemia. Cell. 2012 Jul 20;150(2):264-78. 2012-07-20
Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. Nature. 2012 Jan 11. doi: 10.1038/nature10738. [Epub ahead of print] 2012-01-11
DNMT3A Mutations in Acute Myeloid Leukemia N Engl J Med. 2010 Nov 10. 2010-11-10
Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature. 2010 Apr 15;464(7291):989-90. 2010-04-15
Recurring mutations found by sequencing an acute myeloid leukemia genome. N Engl J Med. 2009 Sep 10;361(11):1058-66. Epub 2009 Aug 5. 2009-09-10