Makedonka Mitreva, Ph.D.,  McDonnell Genome Institute

Dr. Makedonka Mitreva joined Washington University School of Medicine in 2002 and currently is an Associate Professor in both the departments of Medicine and Genetics and serves as Assistant Director of the McDonnell Genome Institute (MGI). She oversees the Department of Microbes, Vectors, and Pathogens at MGI that provides a data management platform and performs comprehensive analysis of omics data (transcriptomes, proteomes, regulomes, genomes, and metagenomes) in a comparative context. Dr. Mitreva is applying integrated approaches to the exploration of multi-omics data, prompting a deeper understanding of an organism at the molecular level.

There are two main threads to Dr. Mitreva’s current research:

• The continued development of molecular information, bioinformatics tools, and reagents for the study of parasitic infections is crucial. Therefore, Dr. Mitreva continues to take advantage of next-generation technologies and implement comparative genomics approaches to study the biology and cellular pathways of these important parasites. This work is accelerating both basic research as well as the development of effective diagnostics, vaccines, and new drugs. Dr. Mitreva and her group make their data available on nematode.net and trematode.net, publicly shared resources dedicated to the study of parasitic helminthes.

• The second area of Dr. Mitreva’s research focuses on the human microbiome (the collection of microbes that colonize the human body) in a functional context. She makes use of computational tools to enable structural and functional characterization of these microbial communities. This comparative metagenomics work will lead to a deeper understanding of how these organisms influence human physiology, nutrition, immunity, and development.

The approaches she is undertaking in these two areas have the potential for significant impact due to the recent explosion in the amount of omics data requiring analysis.

Dr. Mitreva is a leader of the Center for the Clinical Genomics of Microbial Systems (CC-GEMS), a collaboration between MGI and Washington University.

Dr. Mitreva received B.S. and M.S. degrees from Ss. Cyril and Methodius University in Skopje, Macedonia and a Ph.D. from the foremost European center for nematology - Wageningen University and Research Centre (WURC) in The Netherlands.

Publications

title citation publication date
Compartmentalization of functions and predicted miRNA regulation among contiguous regions of the Nematode Intestine. RNA Biol. 2016 Mar 22:0. [Epub ahead of print] 2016-03-22
Dictyocaulus viviparus genome, variome and transcriptome elucidate lungworm biology and support future intervention. Sci Rep. 2016 Feb 9;6:20316. doi: 10.1038/srep20316. 2016-02-09
Characterization of parasite-specific indels and their proposed relevance for selective anthelminthic drug targeting. Infect Genet Evol. 2016 Jan 29. pii: S1567-1348(16)30025-9. doi: 10.1016/j.meegid.2016.01.025. [Epub ahead of print] 2016-01-29
Gene diversity and genetic variation in lung flukes (genus Paragonimus). Trans R Soc Trop Med Hyg. 2016 Jan;110(1):6-12. doi: 10.1093/trstmh/trv101. 2016-01-01
Pan-Nematoda Transcriptomic Elucidation of Essential Intestinal Functions and Therapeutic Targets With Broad Potential. EBioMedicine. 2015 Jul 29;2(9):1079-89. doi: 10.1016/j.ebiom.2015.07.030. eCollection 2015. 2015-07-29
Helminth-induced arginase-1 exacerbates lung inflammation and disease severity in tuberculosis. J Clin Invest. 2015 Dec 1;125(12):4699-713. doi: 10.1172/JCI77378. Epub 2015 Nov 16. 2015-12-01
mBLAST: Keeping up with the sequencing explosion for (meta)genome analysis. J Data Mining Genomics Proteomics. 2015 Aug;4(3). pii: 135. Epub 2013 Jul 31. 2013-01-01
An integrated multi-omics approach to identify candidate antigens for serodiagnosis of human onchocerciasis. Mol Cell Proteomics. 2015 Oct 15. pii: mcp.M115.051953. [Epub ahead of print] 2015-12-01
The Dynamic Genome and Transcriptome of the Human Fungal Pathogen Blastomyces and Close Relative Emmonsia. PLoS Genet. 2015 Oct 6;11(10):e1005493. doi: 10.1371/journal.pgen.1005493. eCollection 2015. 2015-10-06
Targeting Lysine Deacetylases (KDACs) in Parasites. PLoS Negl Trop Dis. 2015 Sep 24;9(9):e0004026. doi: 10.1371/journal.pntd.0004026. eCollection 2015. 2015-09-24
Experimental hookworm infection and escalating gluten challenges are associated with increased microbial richness in celiac subjects. Sci Rep. 2015 Sep 18;5:13797. doi: 10.1038/srep13797. 2015-09-18
The effect of dietary resistant starch type 2 on the microbiota and markers of gut inflammation in rural Malawi children. Microbiome. 2015 Sep 3;3:37. doi: 10.1186/s40168-015-0102-9. 2015-09-03
Metabolic and metagenomic outcomes from early-life pulsed antibiotic treatment. Nat Commun. 2015 Jun 30;6:7486. doi: 10.1038/ncomms8486. 2015-06-30
Cracking the nodule worm code advances knowledge of parasite biology and biotechnology to tackle major diseases of livestock. Biotechnol Adv. 2015 May 27. pii: S0734-9750(15)30003-3. doi: 10.1016/j.biotechadv.2015.05.004. [Epub ahead of print] 2015-05-27
Pan-phylum Comparison of Nematode Metabolic Potential. PLoS Negl Trop Dis. 2015 May 22;9(5):e0003788. doi: 10.1371/journal.pntd.0003788. eCollection 2015. 2015-05-22
Dynamic changes in the subgingival microbiome and their potential for diagnosis and prognosis of periodontitis. MBio. 2015 Feb 17;6(1):e01926-14. doi: 10.1128/mBio.01926-14. 2015-02-17
Functional and phylogenetic characterization of proteins detected in various nematode intestinal compartments. Mol Cell Proteomics. 2015 Jan 21. pii: mcp.M114.046227. [Epub ahead of print] 2015-01-21
Peptidases Compartmentalized to the Ascaris suum Intestinal Lumen and Apical Intestinal Membrane. PLoS Negl Trop Dis. 2015 Jan 8;9(1):e3375. doi: 10.1371/journal.pntd.0003375. eCollection 2015. 2015-01-08
Helminth.net: expansions to Nematode.net and an introduction to Trematode.net. Nucleic Acids Res. 2014 Nov 11. pii: gku1128. [Epub ahead of print] 2014-11-11
Systems biology studies of adult paragonimus lung flukes facilitate the identification of immunodominant parasite antigens. PLoS Negl Trop Dis. 2014 Oct 16;8(10):e3242. doi: 10.1371/journal.pntd.0003242. eCollection 2014. 2014-10-16
Endosymbiont DNA in endobacteria-free filarial nematodes indicates ancient horizontal genetic transfer PLoS One. 2010 Jun 9;5(6):e11029. doi: 10.1371/journal.pone.0011029. 2010-06-09
Genome-wide analysis reveals novel genes essential for heme homeostasis in Caenorhabditis elegans. PLoS Genet. 2010 Jul 29;6(7):e1001044. doi: 10.1371/journal.pgen.1001044. 2010-07-29
A practical, bioinformatic workflow system for large data sets generated by next-generation sequencing. Nucleic Acids Res. 2010 Sep;38(17):e171. doi: 10.1093/nar/gkq667. Epub 2010 Aug 3. 2010-09-01
A systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics. Cell. 2014 Sep 11;158(6):1402-14. doi: 10.1016/j.cell.2014.08.032. 2014-09-11
Proteomics elucidates key molecules involved in exsheathment in vitro in Oesophagostomum dentatum. Int J Parasitol. 2014 Jul 15. pii: S0020-7519(14)00147-7. doi: 10.1016/j.ijpara.2014.06.003. [Epub ahead of print] 2014-07-15
Secreted proteomes of different developmental stages of the gastrointestinal nematode Nippostrongylus brasiliensis. Mol Cell Proteomics. 2014 Jul 3. pii: mcp.M114.038950. [Epub ahead of print] 2014-07-03
Exploration of bacterial community classes in major human habitats. Genome Biol. 2014 May 7;15(5):R66. [Epub ahead of print] 2014-05-07
Mining novel effector proteins from the esophageal gland cells of Meloidogyne incognita. Mol Plant Microbe Interact. 2014 May 29. [Epub ahead of print] 2014-05-29
The prevalence of species and strains in the human microbiome: a resource for experimental efforts. PLoS One. 2014 May 14;9(5):e97279. doi: 10.1371/journal.pone.0097279. eCollection 2014. 2014-05-14
Impact of Experimental Hookworm Infection on the Human Gut Microbiota. J Infect Dis. 2014 May 3. pii: jiu256. [Epub ahead of print] 2014-05-03
Identification and characterization of alternative splicing in parasitic nematode transcriptomes. Parasit Vectors. 2014 Apr 1;7(1):151. doi: 10.1186/1756-3305-7-151. 2014-04-01
Sepsis from the gut: the enteric habitat of bacteria that cause late-onset neonatal bloodstream infections. Clin Infect Dis. 2014 May;58(9):1211-8. doi: 10.1093/cid/ciu084. Epub 2014 Mar 18. 2014-05-01
Genome-Wide Tissue-Specific Gene Expression, Co-expression and Regulation of Co-expressed Genes in Adult Nematode Ascaris suum. PLoS Negl Trop Dis. 2014 Feb 6;8(2):e2678. doi: 10.1371/journal.pntd.0002678. eCollection 2014. 2014-02-06
Analysis of the transcriptome of adult Dictyocaulus filaria and comparison with Dictyocaulus viviparus, with a focus on molecules involved in host-parasite interactions. Int J Parasitol. 2014 Jan 30. pii: S0020-7519(14)00025-3. doi: 10.1016/j.ijpara.2013.12.003. [Epub ahead of print] 2014-01-30
Genome of the human hookworm Necator americanus. Nat Genet. 2014 Jan 19. doi: 10.1038/ng.2875. [Epub ahead of print] 2014-01-19
Precise Dissection of an Escherichia coli O157:H7 outbreak by Single Nucleotide Polymorphism Analysis. J Clin Microbiol. 2013 Sep 18. [Epub ahead of print] 2013-09-18
Exploring the transcriptome of the burrowing nematode Radopholus similis. Mol Genet Genomics. 2008 Jul;280(1):1-17. doi: 10.1007/s00438-008-0340-7. Epub 2008 Apr 2. 2008-07-01
Biology and genome of Trichinella spiralis. WormBook. 2006 Nov 23:1-21. 2006-11-23
Brugia malayi: effects of radiation and culture on gene expression in infective larvae. Mol Biochem Parasitol. 2006 Oct;149(2):201-7. Epub 2006 Jun 22. 2006-10-01
Detection of putative secreted proteins in the plant-parasitic nematode Heterodera schachtii. Parasitol Res. 2006 Apr;98(5):414-24. Epub 2005 Dec 28. 2006-04-01
Comparative genomics of nematodes. Trends Genet. 2005 Oct;21(10):573-81. 2005-10-01
Expressed sequence tags from life cycle stages of Trichinella spiralis: application to biology and parasite control. Vet Parasitol. 2005 Sep 5;132(1-2):13-7. 2005-09-05
An expressed sequence tag analysis of the life-cycle of the parasitic nematode Strongyloides ratti. Mol Biochem Parasitol. 2005 Jul;142(1):32-46. Epub 2005 Apr 18. 2005-07-01
Mining the secretome of the root-knot nematode Meloidogyne chitwoodi for candidate parasitism genes. Mol Plant Pathol. 2008 Jan;9(1):1-10. doi: 10.1111/j.1364-3703.2007.00435.x. 2008-01-01
Nematode gene sequences: update for december 2005. J Nematol. 2005 Dec;37(4):417-21. 2005-12-01
A white paper on nematode comparative genomics. J Nematol. 2005 Dec;37(4):408-16. 2005-12-01
Alpha-gliadin genes from the A, B, and D genomes of wheat contain different sets of celiac disease epitopes. BMC Genomics. 2006 Jan 10;7:1. 2006-01-10
Helminth genomics: The implications for human health. PLoS Negl Trop Dis. 2009 Oct 26;3(10):e538. doi: 10.1371/journal.pntd.0000538. 2009-10-26
Transcriptomes and pathways associated with infectivity, survival and immunogenicity in Brugia malayi L3. BMC Genomics. 2009 Jun 15;10:267. doi: 10.1186/1471-2164-10-267. 2009-06-15
Systematic analysis of insertions and deletions specific to nematode proteins and their proposed functional and evolutionary relevance. BMC Evol Biol. 2009 Jan 28;9:23. doi: 10.1186/1471-2148-9-23. 2009-01-28
NemaPath: online exploration of KEGG-based metabolic pathways for nematodes. BMC Genomics. 2008 Nov 4;9:525. doi: 10.1186/1471-2164-9-525. 2008-11-04
Nematode.net update 2008: improvements enabling more efficient data mining and comparative nematode genomics. Nucleic Acids Res. 2009 Jan;37(Database issue):D571-8. doi: 10.1093/nar/gkn744. Epub 2008 Oct 21. 2009-01-01
Transcription profiling reveals stage- and function-dependent expression patterns in the filarial nematode Brugia malayi. BMC Genomics. 2012 May 14;13:184. doi: 10.1186/1471-2164-13-184. 2012-05-01
Transcripts analysis of the entomopathogenic nematode Steinernema carpocapsae induced in vitro with insect haemolymph. Mol Biochem Parasitol. 2010 Feb;169(2):79-86. doi: 10.1016/j.molbiopara.2009.10.002. Epub 2009 Oct 27. 2010-02-01
Discovery of anthelmintic drug targets and drugs using chokepoints in nematode metabolic pathways. PLoS Pathog. 2013 Aug;9(8):e1003505. doi: 10.1371/journal.ppat.1003505. Epub 2013 Aug 1. 2013-08-01
In-depth Proteomic and Glycomic Analysis of the Adult-Stage Cooperia oncophora Excretome/Secretome. J Proteome Res. 2013 Jul 29. [Epub ahead of print] 2013-07-29
Intestinal transcriptomes of nematodes: comparison of the parasites Ascaris suum and Haemonchus contortus with the free-living Caenorhabditis elegans. PLoS Negl Trop Dis. 2008 Aug 6;2(8):e269. doi: 10.1371/journal.pntd.0000269. 2008-08-01
Nematode gene sequences: update for december 2003. J Nematol. 2003 Dec;35(4):465-9. 2003-12-01
TIMPs of parasitic helminths -- a large-scale analysis of high-throughput sequence datasets. Parasit Vectors. 2013 May 30;6(1):156. [Epub ahead of print] 2013-05-30
Proteomic Analysis of Oesophagostomum dentatum (Nematoda) during Larval Transition, and the Effects of Hydrolase Inhibitors on Development. PLoS One. 2013 May 22;8(5):e63955. doi: 10.1371/journal.pone.0063955. Print 2013. 2013-05-22
Gene expression analysis distinguishes tissue-specific and gender-related functions among adult Ascaris suum tissues. Mol Genet Genomics. 2013 Apr 10. [Epub ahead of print] 2013-04-10
Using existing drugs as leads for broad spectrum anthelmintics targeting protein kinases. PLoS Pathog. 2013 Feb;9(2):e1003149. doi: 10.1371/journal.ppat.1003149. Epub 2013 Feb 14. 2013-02-14
Transcriptome analyses reveal protein and domain families that delineate stage-related development in the economically important parasitic nematodes, Ostertagia ostertagi and Cooperia oncophora. BMC Genomics. 2013 Feb 22;14(1):118. [Epub ahead of print] 2013-02-22
Widespread Colonization of the Lung by Tropheryma whipplei in HIV Infection. Am J Respir Crit Care Med. 2013 Feb 7. [Epub ahead of print] 2013-02-07
An analysis of the transcriptome of Teladorsagia circumcincta: its biological and biotechnological implications. BMC Genomics. 2012;13 Suppl 7:S10. doi: 10.1186/1471-2164-13-S7-S10. Epub 2012 Dec 13. 2012-12-13
Gene expression analysis of ABC transporters in a resistant Cooperia oncophora isolate following in vivo and in vitro exposure to macrocyclic lactones. Parasitology. 2013 Jan 2:1-10. [Epub ahead of print] 2013-01-02
A nuclear single-nucleotide polymorphism (SNP) potentially useful for the separation of Rhodnius prolixus from members of the Rhodnius robustus cryptic species complex (Hemiptera: Reduviidae). Infect Genet Evol. 2012 Dec 5. pii: S1567-1348(12)00352-8. doi: 10.1016/j.meegid.2012.10.018. [Epub ahead of print] 2012-12-05
Genomic variation landscape of the human gut microbiome. Nature. 2012 Dec 5. doi: 10.1038/nature11711. [Epub ahead of print] 2012-12-05
Inter and intra-specific diversity of parasites that cause lymphatic filariasis. Infect Genet Evol. 2012 Nov 29. pii: S1567-1348(12)00342-5. doi: 10.1016/j.meegid.2012.11.002. [Epub ahead of print] 2012-11-29
Silencing of Germline-Expressed Genes by DNA Elimination in Somatic Cells. Dev Cell. 2012 Oct 30. pii: S1534-5807(12)00431-5. doi: 10.1016/j.devcel.2012.09.020. [Epub ahead of print] 2012-10-30
Transcriptomic and Proteomic Analyses of a Wolbachia-Free Filarial Parasite Provide Evidence of Trans-Kingdom Horizontal Gene Transfer. PLoS One. 2012;7(9):e45777. Epub 2012 Sep 26. 2012-09-26
Coverage theories for metagenomic DNA sequencing based on a generalization of Stevens' theorem. J Math Biol. 2012 Sep 11. [Epub ahead of print] 2012-09-11
Metabolic Reconstruction for Metagenomic Data and Its Application to the Human Microbiome. PLoS Comput Biol. 2012 Jun;8(6):e1002358. Epub 2012 Jun 13. 2012-06-13
Exploring metazoan evolution through dynamic and holistic changes in protein families and domains. BMC Evol Biol. 2012 Aug 3;12(1):138. [Epub ahead of print] 2012-08-03
Optimizing read mapping to reference genomes to determine composition and species prevalence in microbial communities. PLoS One. 2012;7(6):e36427. Epub 2012 Jun 13. 2012-06-13
A framework for human microbiome research. Nature. 2012 Jun 13;486(7402):215-21. doi: 10.1038/nature11209. 2012-06-13
Structure, function and diversity of the healthy human microbiome. Nature. 2012 Jun 13;486(7402):207-14. doi: 10.1038/nature11234. 2012-06-13
Effects of Doxycycline on gene expression in Wolbachia and Brugia malayi adult female worms in vivo. J Biomed Sci. 2012 Feb 9;19(1):21. [Epub ahead of print] 2012-02-09
The genome of a blood fluke associated with human cancer. Nat Genet. 2012 Jan 27;44(2):116-8. 2012-01-27
Nematode.net update 2011: addition of data sets and tools featuring next-generation sequencing data. Nucleic Acids Res. 2011 Dec 1. [Epub ahead of print] 2011-12-01
HelmCoP: an online resource for helminth functional genomics and drug and vaccine targets prioritiza PLoS One. 2011;6(7):e21832. Epub 2011 Jul 8. 2011-07-08
Stage-specific excretory-secretory small heat shock proteins from the parasitic nematode Strongyloides ratti--putative links to host's intestinal mucosal defense system. FEBS J. 2011 Sep;278(18):3319-36. doi: 10.1111/j.1742-4658.2011.08248.x. Epub 2011 Aug 24. 2011-08-24
Life cycle stage-resolved proteomic analysis of the excretome/secretome from Strongyloides ratti: Identification of stage-specific protease. Mol Cell Proteomics. 2011 Oct 16. [Epub ahead of print]. 2011-10-16
The transcriptomes of the cattle parasitic nematode Ostertagia ostartagi. Vet Parasitol. 2009 May 26;162(1-2):89-99. Epub 2009 Feb 27. 2009-05-26
Massively parallel sequencing and analysis of the Necator americanus transcriptome. PLoS Negl Trop Dis. 2010 May 11;4(5):e684. 2010-05-11
Deep small RNA sequencing from the nematode Ascaris reveals conservation, functional diversification, and novel developmental profiles. Genome Res. 2011 Jun 17. [Epub ahead of print] 2011-06-17
RNAi Effector Diversity in Nematodes. PLoS Negl Trop Dis. 2011 Jun;5(6):e1176. Epub 2011 Jun 7. 2011-06-07
Targeting protein-protein interactions for parasite control. PLoS One. 2011 Apr 27;6(4):e18381. 2011-04-27
Transcriptome Analysis of Female and Male Xiphophorus maculatus Jp 163 A. PLoS One. 2011 Apr 5;6(4):e18379. 2011-04-05
A vertebrate case study of the quality of assemblies derived from next-generation sequences. Genome Biol. 2011 Mar 31;12(3):R31. [Epub ahead of print] 2011-03-31
The draft genome of the parasitic nematode Trichinella spiralis Nat Genet. 2011 Mar;43(3):228-35. Epub 2011 Feb 20. 2011-02-20
Gender-associated genes in filarial nematodes are important for reproduction and potential intervention targets. PLoS Negl Trop Dis. 2011 Jan 25;5(1):e947. 2011-01-25
Deep insights into Dictyocaulus viviparus transcriptomes provides unique prospects for new drug targets and disease intervention. Biotechnol Adv. 2010 Dec 22. 2010-12-22
Comparative and demographic analysis of orang-utan genomes Nature. 2011 Jan 27;469(7331):529-33. 2011-01-27
First transcriptomic analysis of the economically important parasitic nematode, Trichostrongylus colubriformis, using a next-generation sequencing approach. Infect Genet Evol. 2010 Dec;10(8):1199-207. Epub 2010 Aug 6. 2010-12-01
Identification of hookworm DAF-16/FOXO response elements and direct gene targets. PLoS One. 2010 Aug 19;5(8):e12289. 2010-08-19
Novel venom gene discovery in the platypus. Genome Biol. 2010;11(9):R95. Epub 2010 Sep 29. 2010-09-29
Trichinella Spiralis: genomic application to control a zoonotic Infect Disord Drug Targets. 2010 Oct 1;10(5):376-84. 2010-10-01
Characterizing Ancylostoma caninum transcriptome and exploring nematode parasitic adaptation. BMC Genomics. 2010 May 14;11:307. 2010-05-14
A Catalog of Reference Genomes from the Human Microbiome. Science. 2010 May 21;328(5981):994-999. 2010-05-21
Expressed sequence tags of the peanut pod nematode Ditylenchus africanus: The first transcriptome analysis of an Anguinid nematode. Mol Biochem Parasitol. 2009 Apr [Epub ahead of print] 2009-04-01
Role of horizontal gene transfer in the evolution of plant parasitism among nematodes. Methods Mol Biol. 2009;532:517-35. Review. 2009-01-01
Molecular determinants archetypical to the phylum Nematoda. BMC Genomics. 2009 Mar 18;10:114. 2009-03-18
Integrating genomics and phylogenetics in understanding the history of Trichinella species. Vet Parasitol. 2009 Feb 23;159(3-4):210-3. Epub 2008 Oct 22. 2008-10-22
Sequence mining and transcript profiling to explore cyst nematode parasitism. BMC Genomics. 2009 Jan 30;10:58. 2009-01-30
Large-Scale Sequencing and Analytical Processing of ESTs. Methods Mol Biol. 2009;533:1-35. 2009-01-01
Strategies for Undertaking Expressed Sequence Tag (EST) Projects. Methods Mol Biol. 2009;533:1-20. 2009-01-01
The Pristionchus pacificus genome provides a unique perspective on nematode lifestyle and parasitism. Nat Genet. 2008 Oct;40(10):1193-8. Epub 2008 Sep 21. 2008-10-01
Advances in the sequencing of the genome of the adenophorean nematode Trichinella spiralis. Parasitology. 2008 Jul;135(8):869-80. 2008-07-26
Genome analysis of the platypus reveals unique signatures of evolution. Nature. 2008 May 8;453(7192):175-83. 2008-05-08
The canine hookworm genome: analysis and classification of Ancylostoma caninum survey sequences. Mol Biochem Parasitol. 2008 Feb;157(2):187-92. Epub 2007 Nov 9. 2008-02-15
The bandit, a New DNA Transposon from a Hookworm-Possible Horizontal Genetic Transfer between Host and Parasite. PLoS Negl Trop Dis. 2007 Sep 27;1(1):e35. 2007-09-26
Parasitic nematodes - from genomes to control. Vet Parasitol. 2007 Aug 19;148(1):31-42. Epub 2007 Jun 7. 2007-08-19
Draft genome of the filarial nematode parasite Brugia malayi. Science. 2007 Sep 21;317(5845):1756-60. 2007-09-21
Divergent evolution of arrested development in the dauer stage of Caenorhabditis elegans and the infective stage of Heterodera glycine. Genome Biol. 2007 Oct 5;8(10):R211 [Epub ahead of print] 2007-10-05
Investigating hookworm genomes by comparative analysis of two Ancylostoma species. BMC Genomics. 2005 Apr 26;6(1):58. 2005-04-26
Identification and analysis of genes expressed in the adult filarial parasitic nematode Dirofilaria immitis. Int J Parasitol. 2006 Jun;36(7):829-39. Epub 2006 Mar 31. 2006-03-15
Profiling of gender-regulated gene transcripts in the filarial nematode Brugia malayi by cDNA oligonucleotide array analysis. Mol Biochem Parasitol. 2005 Sep;143(1):49-57. 2005-08-31
Analysis and functional classification of transcripts from the nematode Meloidogyne incognita. Genome Biol. 2003;4(4):R26. Epub 2003 Mar 31. 2003-03-31
Comparative genomics of gene expression in the parasitic and free-living nematodes Strongyloides stercoralis and Caenorhabditis elegans. Genome Res. 2004 Feb;14(2):209-20. 2004-02-01
Nematode.net: a tool for navigating sequences from parasitic and free-living nematodes. Nucleic Acids Res. 2004 Jan 1;32 Database issue:D423-6. 2004-01-01
A transcriptomic analysis of the phylum Nematoda Nat Genet. 2004 Dec;36(12):1259-67. Epub 2004 Dec. 2004-11-14
A survey of SL1-spliced transcripts from the root-lesion nematode Pratylenchus penetrans. Mol Genet Genomics. 2004 Sep;272(2):138-48. Epub 2004 Aug 28. 2004-09-01
mRNA sequences for Haemonchus contortus intestinal cathepsin B-like cysteine proteases display an extreme in abundance and diversity compared with other adult mammalian parasitic nematodes. Mol Biochem Parasitol. 2004 Oct;137(2):297-305. 2004-10-23
Gene discovery in the adenophorean nematode Trichinella spiralis: an analysis of transcription from three life cycle stages. Mol Biochem Parasitol. 2004 Oct;137(2):277-91. 2004-10-25
400000 nematode ESTs on the Net. Trends Parasitol. 2003 Jul;19(7):283-6. 2003-06-01