Patrick Minx
Research Accomplishments & Interests
Pat Minx, M.S., joined The Genome Institute in 1994 as a member of the finishing group. Currently he is a Group Leader and manages the large genome assembly, microbial assembly, submissions and screening groups. He focuses on maximizing accuracy and contiguity of sequence assemblies through program automation.
Other Biographical Information
Mr. Minx received his Bachelor of Science degree from the University of Missouri in Forestry, Fisheries and Wildlife, and a Master's Degree in Biology from the University of Missouri - St. Louis. He is also interested in the research fields of phylogenetic reconstruction and herpetology.
Selected Publications
Swart EC, Nowacki M, Shum J, Stiles H, Higgins BP, Doak TG, Schotanus K, Magrini…
The Oxytricha trifallax mitochondrial genome.
Genome Biol Evol. 2011 Dec 16. [Epub ahead of print] PubMed | View Abstract
Yao G, Ye L, Gao H, Minx P, Warren WC, Weinstock GM.
Graph accordance of next-generation sequence assemblies.
Bioinformatics. 2011 Oct 23. [Epub ahead of print] PubMed | View Abstract
Lindblad-Toh K, Garber M, Zuk O, Lin MF, Parker BJ, Washietl S, Kheradpour P, Ernst…
A high-resolution map of human evolutionary constraint using 29 mammals.
Nature. 2011 Oct 12;478(7370):476-82. doi: 10.1038/nature10530. PubMed | View Abstract
Jung S, Swart EC, Minx PJ, Magrini V, Mardis ER, Landweber LF, Eddy SR.
Exploiting Oxytricha trifallax nanochromosomes to screen for non-coding RNA genes.
Nucleic Acids Res. 2011 Jun 28. [Epub ahead of print] PubMed | View Abstract
Ye L, Hillier LW, Minx P, Thane N, Locke D, Martin JC, Chen L, Mitreva…
A vertebrate case study of the quality of assemblies derived from next-generation sequences.
Genome Biol. 2011 Mar 31;12(3):R31. [Epub ahead of print] PubMed | View Abstract
Mitreva M, Jasmer DP, Zarlenga DS, Wang Z, Abubucker S, Martin J, Taylor CM, Yin…
The draft genome of the parasitic nematode Trichinella spiralis
Nature Genetics 2011 doi:10.1038/ng.769 PubMed | View Abstract
Locke DP, Hillier LW, Warren WC, Worley KC, Nazareth LV, Muzny DM, Yang SP, Wang…
Comparative and demographic analysis of orang-utan genomes
Nature. 2011 Jan 27;469(7331):529-33. PubMed | View Abstract
Baxter L, Tripathy S, Ishaque N, Boot N, Cabral A, Kemen E, Thines M, Ah-Fong…
Signatures of adaptation to obligate biotrophy in the Hyaloperonospora arabidopsidis genome.
Science. 2010 Dec 10;330(6010):1549-51. PubMed | View Abstract
Lawniczak MK, Emrich SJ, Holloway AK, Regier AP, Olson M, White B, Redmond S, Fulton…
Widespread Divergence Between Incipient Anopheles gambiae Species Revealed by Whole Genome Sequences.
Science. 2010 Oct 22;330(6003):512-4. PubMed | View Abstract
The Human Microbiome Jumpstart Reference Strains Consortium, Nelson KE, Weinstock GM, Highlander SK, Worley KC,…
A Catalog of Reference Genomes from the Human Microbiome.
Science. 2010 May 21;328(5981):994-999. PubMed | View Abstract
Warren WC, Clayton DF, Ellegren H, Arnold AP, Hillier LW, Künstner A, Searle S, White…
The genome of a songbird.
Nature. 2010 Apr 1;464(7289):757-62. PubMed | View Abstract
Kucerova E, Clifton SW, Xia XQ, Long F, Porwollik S, Fulton L, Fronick C, Minx…
Genome sequence of Cronobacter sakazakii BAA-894 and comparative genomic hybridization analysis with other Cronobacter species.
PLoS One. 2010 Mar 8;5(3):e9556. PubMed | View Abstract
Hughes JF, Skaletsky H, Pyntikova T, Graves TA, van Daalen SK, Minx PJ, Fulton RS,…
Chimpanzee and human Y chromosomes are remarkably divergent in structure and gene content.
Nature. 2010 Jan 28;463(7280):536-9. Epub 2010 Jan 13. PubMed | View Abstract
Schnable PS, Ware D, Fulton RS, Stein JC, Wei F, Pasternak S, Liang C, Zhang…
The B73 maize genome: complexity, diversity, and dynamics.
Science. 2009 Nov 20;326(5956):1112-5. PubMed | View Abstract
Ley TJ, Mardis ER, Ding L, Fulton B, McLellan MD, Chen K, Dooling D, Dunford-Shore…
DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome.
Nature. 2008 Nov 6;456(7218):66-72. PubMed | View Abstract
