Project

Washington University Cancer Genome Initiative

The primary aim of the Washington University Cancer Genome Initiative (WUCGI) is to sequence the tumor and normal genomes from 150 cancer patients (for a total of 300 complete genomes).

Washington University Cancer Genome Initiative Details

Started in April 2009 at the McDonnell Genome Institute at Washington University, the initiative has succeeded in increasing the efficiency and reducing the cost of whole genome sequencing, while further developing the informatics tools required to analyze these data and find the genetic events that underlie cancer.

The types of cancers that have been sequenced include Acute Myeloid Leukemia (AML), breast, lung, brain, prostate, pancreatic, multiple myeloma and ovarian cancers. By comparing both the tumor and normal DNA of these patients, WUCGI is helping researchers understand those changes in the genome that lead to the development of cancer and provide more personalized diagnoses and treatments.

Find out more about the impact of the Washington University Cancer Genome Initiative.