Construction of the Physical Map of Homo sapiens
--------------------------------------------------------------------

The physical map of Homo sapiens was constructed by generating fingerprints
from several BAC libraries, but mostly RPCI-11 and RPCI-13
(http://bacpac.chori.org), and CalTech B, C, and D
(http://informa.bio.caltech.edu/idx_www_tree.html) libraries.  The map consists
of 415,801 BAC clones with an average insert size of 172kb.  The clones were
digested and run on agarose gels to produce fingerprints, analyzed with Image
(http://www.sanger.ac.uk/Software/Image), and assembled in an FPC database
(http://www.agcol.arizona.edu/software/fpc/). The assembled contigs were
manually edited to achieve proper order based upon fingerprint banding patterns
and were then merged with one another to generate the largest contigs possible.
Contigs within the map database have been numbered with respect to their
position along the chromosome beginning with the first contig in the cytogenetic
band.  The first digit (or two digits) represents the chromosome that the contig
is anchored to. A '9' in the second digit (or third digit) location indicates an
unanchored contig on that chromosome.  For example, chromosome 1 contigs are
numbered from 1001-1048 and the unanchored contigs on chromosome 1 are from
1949-1959. Chromosome X contigs start with 23, chromosome Y with 24 and
unlocalized contigs with 25.  The physical map currently consists of 528 contigs.
This physical map is a work-in-progress and as such is subject to change as edits
are needed.  Occasional updates of the database will be made available.

This map was built and edited with FPC Version 5.0

HumanMap.tar.gz 
    * Bands
	-The original mobility values.
    * Sizes
	-The base pair conversion of each band based on a standard.
    * Gel
	-The actual gel images processed by Image.
    * HumanMap.fpc
    * HumanMap.cor
    * HumanMap.fpp

HumanMap.fpc.gz 	Main Fpc text file that contains clone, contig, marker,
                        and Fpc map data.
HumanMap.cor.gz 	Binary file used by Fpc to map clones to bands for
                        sulston score calculations.
HumanMap.fpp.gz 	Fpc interface preferences file.

The last three FPC files are part of the larger tarball, but are also made
available as individual compressed files for users not interested in the raw data,
i.e., Gels, Bands, Sizes.

The name conversions are as follows:
FPC     =>      NCBI
---------------------
F	=>	RP13
N	=>	RP11
G	=>	GS1(1-378)
M	=>      CTB(1-194), CTC(195-879), CTD1(2001-2423)
D	=>      CTD2(2501-3254)
None	=>	PAC libraries - RP1(1-321), RP3(322-528), RP4(529-816),
                RP5(817-1200), RP6(1-240)
R	=>	CTA or CTB
A	=>      Whitehead clones	
AE	=>	LLNL Ch. 7 Cosmid 
AF	=>	LANL Ch. 4 Cosmid
AG	=>	LLNL Ch. 2 Fosmid
AH	=>	LLNL Ch. 2 Cosmid


WUGSC uses the Fpc sequence tags to color code sequenced clones.  The conversion of the Fpc
sequence tags to WUGSC sequnce status is as follows.  This is not useful to most users outside WUGSC.
Fpc Sequence Type => WUGSC Clone Status
-------------------------------------
HALF_X  =>      'inactive'
FULL_X  =>      'active' or 'pre oracle'
NONE    =>      'mapping'

Fpc Sequence Status => WUGSC Project Status
-----------------------------------------
CANCELLED       =>      'redundant'
FINISHED        =>      'submitted'
SHOTGUN         =>      all other project status (ie. 'shotgun done', 'prefinish', etc.)
SENT            =>      null