Publication

BreakPoint Surveyor: A Pipeline for Structural Variant Visualization

Bioinformatics. 2017 Jun 5. doi: 10.1093/bioinformatics/btx362

Abstract

Summary:

BreakPoint Surveyor (BPS) is a computational pipeline for the discovery, characterization, and visualization of complex genomic rearrangements, such as viral genome integration, in paired-end sequence data. BPS facilitates interpretation of structural variants by merging structural variant breakpoint predictions, gene exon structure, read depth, and RNA-Seq expression into a single comprehensive figure.

Availability:

Source code and sample data freely available for download at https://github.com/ding-lab/BreakPointSurveyor , distributed under the GNU GPLv3 license, implemented in R, Python, and BASH scripts, and supported on Unix/Linux/OS X operating systems.

Contact:

m.wyczalkowski@wustl.edu.

Supplementary information:

Supplementary data and figures are available at Bioinformatics online.

Authors

Wyczalkowski MA1,2, Wylie KM2,3, Cao S1,2, McLellan MD2, Flynn J4, Huang M1,2, Ye K2, Fan X5, Chen K5, Wendl MC1,2,4,6, Ding L1,2,4,7.