Capillary electrophoresis platforms for DNA sequence analysis.

J Biomol Tech. 1999 Sep;10(3):137-43.


Commercial availability of multicapillary DNA sequencing instruments can significantly impact the existing paradigm in high-throughput DNA sequencing facilities, shifting the rate-limiting step away from the electrophoresis and detection step. These instruments, although novel and poorly understood, represent a significant capital investment.This review informs the reader about the state-of-the-art instruments, although capillary sequencers are in a state of almost constant flux, with improvements emerging rapidly.


Mardis ER.

Institute Authors