Publication

ChimeraScan: a tool for identifying chimeric transcription in sequencing data.

Bioinformatics. 2011 Oct 15;27(20):2903-4. doi: 10.1093/bioinformatics/btr467. Epub 2011 Aug 11.

Abstract

SUMMARY: Next generation sequencing (NGS) technologies have enabled de novo gene fusion discovery that could reveal candidates with therapeutic significance in cancer. Here we present an open-source software package, ChimeraScan, for the discovery of chimeric transcription between two independent transcripts in high-throughput transcriptome sequencing data.
AVAILABILITY: http://chimerascan.googlecode.com
CONTACT: cmaher@dom.wustl.edu
SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

Authors

Iyer MK, Chinnaiyan AM, Maher CA.

Institute Authors

Christopher Maher, Ph.D.