Organizing knowledge to enable personalization of medicine in cancer.

Genome Biol. 2014 Aug 27;15(8):438. [Epub ahead of print]


Interpretation of the clinical significance of genomic alterations remains the most severe bottleneck preventing the realization of personalized medicine in cancer. We propose a knowledge commons to facilitate collaborative contributions and open discussion of clinical decision-making based on genomic events in cancer.


Good BM, Ainscough BJ, McMichael JF, Su AI, Griffith OL.