Using SomaticSniper to Detect Somatic Single Nucleotide Variants.

Curr Protoc Bioinformatics. 2014 Mar 21;15(155):15.5.1-15.5.8.


Detecting somatic single nucleotide variants (SNVs) is an essential component of cancer research with next generation sequencing data. This protocol describes how to run the SomaticSniper somatic SNV detector and then filter the output to eliminate most false positives. It also includes support protocols detailing the compilation of the software.


Larson DE, Abbott TE, Wilson RK.

Institute Authors

David Larson, Ph.D.