ComComb
Version: 1.0
What it does:
A perl script for cross tumor analysis. It finds the most common gene combinations in different cancer types. It also finds the most frequently mutated genes in each cancer type and their frequencies in all cancer types.
Author: Xiaoqi Shi (xshi@wustl.edu), The Genome Institute, Washington University in St. Louis
Usage
(currently only available for TGI users)
- ComComb.pl in.mut.file minM minC maxC report the gene combination mutation frequency for each cancer type as well as the most mutated genes
- ComComb_mlc.pl minC maxC get the mutated gene or gene combination frequencies across all cancer types
Notes:
- in.mut.file should be a comma delimited file and the first and second columns are the gene and sample names.
- minM indicate the minimum mutation rate for a gene
- minC and maxC give the range of how many gene combinations that user would like the program to analyze
