Semblance
Assess a genome assembly by comparison to finished clones.
Package
- category: assembly::quality control
- operating system: OS independent (Perl)
- license: GNU GPL
- project administrator: Dave Messina
- download: semblance
Application: Bioinformatics
Semblance will compare a genome assembly to finished clones and produce an evaluation of the assembly in terms of a number of metrics, such as:
- Discrepancies (substitutions, deletions, insertions)
- Coverage (of the clone by the assembly)
- Interruptions (of a supercontig by another supercontig)
There are three major phases to semblance: BLASTs of each finished clone against the assembly contigs, refining those alignments with cross_match, and then analyzing the alignments according to the various analysis metrics.
