Michael C. Wendl

Education and Training

• Postdoctoral Trainee, Washington University School of Medicine (1994-1997)

• Doctor of Science, Engineering and Applied Science, Washington University (1994)

• Master of Science, Mechanical Engineering, Washington University (1990)

• Bachelor of Science, Mechanical Engineering, Washington University (1989).

Published Research (Journal Articles in Print)

1. Wendl, M. C., Smith, S., Pohl, C. S., Dooling, D. J., Chinwalla, A. T., Crouse, K., Hepler, T., Leong, S., Carmichael, L., Nhan, M., Oberkfell, B. J., Mardis, E. R., Hillier, L. W., and Wilson, R. K. (2007) ``Design and Implementation of a Generalized Laboratory Data Model'', BMC Bioinformatics, 8 (article number 362). Pubmed (PMID 17897463)

2. Wendl, M. C. (2007) ``Algebraic Correction Methods for Computational Assessment of Clone Overlaps in DNA Fingerprint Mapping'', BMC Bioinformatics, 8 (article number 127). Pubmed (PMID 17442113)

3. Chen, K., McLellan, M. D., Ding, L., Wendl, M. C., Kasai, Y., Wilson, R. K., and Mardis, E. R. (2007) ``PolyScan: Automatic Indel and SNP Detection in Human Resequence Data'', Genome Research, 17 (5), 659-666. Pubmed (PMID 17416743)

4. Mitreva, M., Wendl, M. C., Martin, J., Wylie, T., Yin, Y., Larson, A., Parkinson, J., Waterston, R. H., and McCarter, J. P. (2006) ``Codon Usage Patterns in Nematoda: Analysis Based on Over 25 Million Codons in Thirty-Two Species'', Genome Biology, 7 (article number 75). Pubmed (PMID 16907990)

5. Wendl, M. C. (2006) ``A General Coverage Theory for Shotgun DNA Sequencing'', Journal of Computational Biology, 13 (6), 1177-1196. Pubmed (PMID 16901236)

6. Wendl, M. C. (2006) ``Occupancy Modeling of Coverage Distribution for Whole Genome Shotgun DNA Sequencing'', Bulletin of Mathematical Biology, 68 (1), 179-196. Pubmed (PMID 16794926)

7. Wendl, M. C. and Barbazuk, W. B. (2005) ``Extension of Lander-Waterman Theory for Sequencing Filtered DNA Libraries'', BMC Bioinformatics, 6 (article number 245). Pubmed (PMID 16216129)

8. Mikkelsen, T. J. et al. (2005) ``Initial Sequence of the Chimpanzee Genome and Comparison with the Human Genome'', Nature, 437 (7055), 69-87. Pubmed (PMID 16136131)

9. Wendl, M. C. (2005) ``Probabilistic Assessment of Clone Overlaps in DNA Fingerprint Mapping via a priori Models'', Journal of Computational Biology, 12 (3), 283-297. Pubmed (PMID 15857243)

10. Hillier, L. W., et al. (2005) ``Generation and Annotation of the DNA Sequences of Human Chromosomes 2 and 4'', Nature, 434 (7034), 724-731. Pubmed (PMID 15815621)

11. International Human Genome Sequencing Consortium [Z. Abdellah, et al.] (2004) ``Finishing the Euchromatic Sequence of the Human Genome'', Nature, 431 (7011), 931-945. Pubmed (PMID 15496913)

12. Wendl, M. C. and Yang, S. P. (2004) ``Gap Statistics for Whole Genome Shotgun DNA Sequencing Projects'', Bioinformatics, 20 (10), 1527-1534. Pubmed (PMID 14962917)

13. Wendl, M. C. (2003) ``Collision Probability Between Sets of Random Variables'', Statistics & Probability Letters, 64 (3), 249-254.

14. Hillier, L. W., et al. (2003) ``The DNA Sequence of Human Chromosome 7'', Nature, 424 (6945), 157-164. Pubmed (PMID 12853948)

15. Wendl, M. C. and Waterston, R. H. (2002) ``Generalized Gap Model for Bacterial Artificial Chromosome Clone Fingerprint Mapping and Shotgun Sequencing'', Genome Research, 12 (12), 1943-1949. Pubmed (PMID 12466299)

16. Waterston, R. H. et al. (2002) ``Initial Sequencing and Comparative Analysis of the Mouse Genome'', Nature, 420 (6915), 520-562. Pubmed (PMID 12466850)

17. Wendl, M. C. and Agarwal, R. K. (2002) ``Viscous Dissipation in Finite Thin-Gap Couette Devices'', Journal of Heat Transfer, 124 (1), 200-203.

18. Wendl, M. C. (2001) ``Mathematical Analysis of Coaxial Disk Cellular Shear Loading Devices'', Review of Scientific Instruments, 72 (11), 4212-4217.

19. Wendl, M. C., Marra, M. A., Hillier, L. W., Chinwalla, A. T., Wilson, R. K., and Waterston, R. H. (2001) ``Theories and Applications for Sequencing Randomly Selected Clones'', Genome Research, 11 (2), 274-280. Pubmed (PMID 11157790)

20. Wendl, M. C., Korf, I., Chinwalla, A. T., and Hillier, L. W. (2001) ``Automated Processing of Raw DNA Sequence Data'', IEEE Engineering in Medicine and Biology, 20 (4), 41-48. Pubmed (PMID 11494768)

21. Lander, E. S. et al. (2001) ``Initial Sequencing and Analysis of the Human Genome'', Nature, 409 (6822), 860-921. Pubmed (PMID 11237011)

22. Wendl, M. C. and Agarwal, R. K. (2000) ``Couette Flow Profiles for Two Non-Classical Taylor-Couette Cells'', Journal of Fluids Engineering, 122 (2), 435-438.

23. Wendl, M. C. (1999) ``General Solution for the Couette Flow Profile'', Physical Review E, 60 (5), 6192-6194. Pubmed (PMID 11970531)

24. Wendl, M. C. (1999) ``A Method for Obtaining Benchmark Navier-Stokes Solutions'', International Journal for Numerical Methods in Fluids, 31 (3), 657-660.

25. C. elegans Sequencing Consortium [R. H. Waterston, et al.] (1998) ``Genome Sequence of the Nematode C. elegans: A Platform for Investigating Biology'', Science, 282 (5396), 2012-2018. Pubmed (PMID 9851916)

26. Wendl, M. C., Dear, S., Hodgson, D., and Hillier, L. (1998) ``Automated Sequence Preprocessing in a Large-Scale Sequencing Environment'', Genome Research, 8 (9), 975-984. Pubmed (PMID 9750196)

27. Ewing, B., Hillier, L., Wendl, M. C., and Green, P. (1998) ``Base-calling of Automated Sequencer Traces Using PHRED. I. Accuracy Assessment'', Genome Research, 8 (3), 175-185. Pubmed (PMID 9521921)

Book Chapters

1. Wendl, M. C., Wallis, J. W., Yang, S. P., Chinwalla, A. T. and Hillier, L. W. (2005) ``Genome Assembly'', In Encyclopedia of Genetics, Genomics, Proteomics, and Bioinformatics, Edited by P. F. R. Little, John Wiley & Sons, Volume 3, pp. 1047-1058.

2. Wendl, M. C., Fulton, R. S., Graves, T., Mardis, E. R., and Wilson, R. K. (2005) ``The Mouse Genome Sequencing Project: An Overview'', Ch. 16 in The Mouse in Animal Genetics and Breeding Research, Edited by E. J. Eisen, World Scientific, New Jersey, U. S. A., pp. 341-352.

3. Wendl, M. C., Chinwalla, A. T., and Hillier, L. W. (2003) ``Software for Genomic Sequencing'', Ch. 12 in Genome Mapping and Sequencing, Edited by I. Dunham, Horizon Scientific Press, Wymondham Norfolk, U. K., pp. 357-395.

4. Wendl, M. C. and Agarwal, R. K. (2003) ``Mass Conservation and the Accuracy of Non-Staggered Grid Incompressible Flow Schemes'', In Numerical Simulations of Incompressible Flows, Edited by M. M. Hafez, World Scientific, New Jersey, U. S. A. pp. 86-97.

5. Wendl, M. C. (2001) ``Mathematics and Numeracy'', In Encyclopedia of the United States in the Nineteenth Century, Edited by P. Finkelman, Charles Scribner's Sons, New York, U. S. A. Volume 2, pp. 273-274.

Op-Ed Pieces

1. Wendl, M. C. (2007) ``H-Index: However Ranked, Citations Need Context'', Nature, 449 (7161), 403. Pubmed (PMID 17898746)

2. Wendl, M. C. (2005) ``Bioweapons Could Kill More in One Strike than Guns'', Nature, 437 (7056), 192. Pubmed (PMID 16148911)

3. Wendl, M. C. (2005) ``The Question of Forbidden Knowledge'', Science, 308 (5728), 1549. Pubmed (PMID 15957206)

4. Wendl, M. C. and Dooling, D. J. (2003) ``Open-Source Answer to Bibliography Problem'', Nature, 424 (6952), 995. Pubmed (PMID 12944940)

5. Wendl, M. C. (1997) ``Computer Testing Not Yet Mature'', American Physical Therapy Association Bulletin, 12 (16), 16.

back to Michael Wendl homepage