Genomics Video Gallery
Decoding Breast Cancer Tumors
Scientists at Washington University School of Medicine's Genome Institute have decoded the genome of an African-American woman with a lethal "triple-negative" breast tumor, along with the genomes of her breast tumor and a tumor that spread to her brain. By comparing the three genomes, they identified the mutations in the primary breast tumor that likely drove the metastasis. By sequencing additional genomes of breast cancer patients with the same type of breast cancer, the researchers hope to develop a genetic profile for this tumor type that can lead to more effective, targeted treatments.
