Scientific Excellence

Unparalleled Experience

Superior Technology

Offering a Full Suite of Multi-Omic Services


The McDonnell Genome Institute has been at the forefront of genomics research since our central role in the Human Genome Project. Built to deliver results on time and on budget, MGI thrives on difficult projects.

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Genomics

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Functional Genomics

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Mass Spectrometry

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Functional Imaging

Our High-Capacity Technology Hubs

Genome Technology Access Center


  • Short-read sequencing
  • Long-read sequencing
  • High-throughput proteomics
  • Single cell genomics
  • Spatial transcriptomics
  • Computational biology/bioinformatics

Genome Engineering & Stem Cell Center


  • Genome-edited stem cell & cancer cell lines
  • Genome-edited model organisms
  • Patient-derived iPSCs
  • Stem cell differentiation
  • CRISPR screening

Mass Spectrometry Technology Access Center


  • Proteomics
  • Metabolomics
  • Lipidomics
  • Deep-scale PTM analysis
  • Native Mass Spectrometry
  • Spatial multi-omics MS technologies

Functional Imaging for Variant Elucidation


  • Massively parallel genetic cellular screening
  • Drug screening
  • Isolating Live cells from Specific Phenotypes
  • Spatial Transcriptomics Image Analysis

Built For Your Success


MGI is a world leader in genomics with a wide breadth of technologies and a rich history of collaborations through well-established sharing and outreach pipelines. Our work is particularly unique due to the breadth of resources we offer in one location.

16

Years MGI Employee Tenure

95%

% Repeat Partner Rate

65

Current Academic Institute Partners

56

Current Biopharma Partners

Clinical OMICS: Where Multi-Omics Meets Clinical Reality

Clinical OMICS: Where Multi-Omics Meets Clinical Reality

June 11, 2025 Multi-omic technologies have expanded rapidly over the past two decades. Researchers now have access to whole genome sequencing, spatial transcriptomics, proteomics, metabolomics, and more—all capable of capturing different aspects of disease biology. These tools have led to important discoveries, but they’ve also introduced new challenges: data fragmentation, inconsistent interpretation, and findings that […]

Regulatory Evolution in the Wild

Evolution, genetics, single-cell genomics, biochemistry… this story of parrot pigments has it all. November 11, 2024 One of the significant findings of the past few decades in genomics is that animal species, despite their vast differences in morphology, physiology, and behavior, share more or less the same repertoire of genes. What truly distinguishes humans from […]
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