Scientific Excellence

Unparalleled Experience

Superior Technology

Offering a Full Suite of Multi-Omic Services


The McDonnell Genome Institute has been at the forefront of genomics research since our central role in the Human Genome Project. Built to deliver results on time and on budget, MGI thrives on difficult projects.

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Genomics

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Functional Genomics

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Mass Spectrometry

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Functional Imaging

Help Shape the 2024 Multi-Omic Fee-for-Service Report!

Participate in our survey and contribute to the inaugural 2024 Multi-omic Fee-for-Service Report. Share your insights and help define the trends driving the field.

Not getting the response levels we expected in late-stage development, we pivoted and partnered with MGI. Their protocols identified a more predictive molecular fingerprint that we simply wouldn’t have uncovered ourselves.

Lead Investigator,
Fortune 500 Biopharma Company

MGI’s services are not only comprehensive but also incredibly service-oriented, showcasing their deep expertise. Working with them eliminates the need for us to constantly track the latest technologies ourselves, allowing us to focus on the success of our project. Their practical expertise and dedication made our collaboration seamless and highly rewarding.

WashU Medicine
Principal Investigator
Professor of Pediatrics, Professor of Pathology and Immunology
Megan Cooper, MD, PhD

Our High-Capacity Technology Hubs

Genome Technology Access Center


  • Short-read sequencing
  • Long-read sequencing
  • High-throughput proteomics
  • Single cell genomics
  • Spatial transcriptomics
  • Computational biology/bioinformatics

Genome Engineering & Stem Cell Center


  • Genome-edited stem cell & cancer cell lines
  • Genome-edited model organisms
  • Patient-derived iPSCs
  • Stem cell differentiation
  • CRISPR screening

Mass Spectrometry Technology Access Center


  • Proteomics
  • Metabolomics
  • Lipidomics
  • Deep-scale PTM analysis
  • Native Mass Spectrometry
  • Spatial multi-omics MS technologies

Functional Imaging for Variant Elucidation


  • Massively parallel genetic cellular screening
  • Drug screening
  • Isolating Live cells from Specific Phenotypes
  • Spatial Transcriptomics Image Analysis

Built For Your Success


MGI is a world leader in genomics with a wide breadth of technologies and a rich history of collaborations through well-established sharing and outreach pipelines. Our work is particularly unique due to the breadth of resources we offer in one location.

16

Years MGI Employee Tenure

95%

% Repeat Partner Rate

65

Current Academic Institute Partners

56

Current Biopharma Partners

Regulatory Evolution in the Wild

Evolution, genetics, single-cell genomics, biochemistry… this story of parrot pigments has it all. November 11, 2024 One of the significant findings of the past few decades in genomics is that animal species, despite their vast differences in morphology, physiology, and behavior, share more or less the same repertoire of genes. What truly distinguishes humans from […]

When are Foundation Models Not the Answer?

Genomic large language models can be impressive, but we need ‘on-device’ data-efficient deep learning strategies to tackle all human cell types. November 18, 2024 Seeing the light at the end of an LLM tunnel Apple recently rolled out Apple Intelligence, their version of deep learning tools designed to be “AI for the rest of us.” Generative […]
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