Scientific Excellence

Unparalleled Experience

Superior Technology

Offering a Full Suite of Multi-Omic Services


The McDonnell Genome Institute has been at the forefront of genomics research since our central role in the Human Genome Project. Built to deliver results on time and on budget, MGI thrives on difficult projects.

Your Page Title

Genomics

Your Page Title

Functional Genomics

Your Page Title

Mass Spectrometry

Your Page Title

Functional Imaging

Our High-Capacity Technology Hubs

Genome Technology Access Center


  • Short-read sequencing
  • Long-read sequencing
  • High-throughput proteomics
  • Single cell genomics
  • Spatial transcriptomics
  • Computational biology/bioinformatics

Genome Engineering & Stem Cell Center


  • Genome-edited stem cell & cancer cell lines
  • Genome-edited model organisms
  • Patient-derived iPSCs
  • Stem cell differentiation
  • CRISPR screening

Mass Spectrometry Technology Access Center


  • Proteomics
  • Metabolomics
  • Lipidomics
  • Deep-scale PTM analysis
  • Native Mass Spectrometry
  • Spatial multi-omics MS technologies

Functional Imaging for Variant Elucidation


  • Massively parallel genetic cellular screening
  • Drug screening
  • Isolating Live cells from Specific Phenotypes
  • Spatial Transcriptomics Image Analysis

Built For Your Success


MGI is a world leader in genomics with a wide breadth of technologies and a rich history of collaborations through well-established sharing and outreach pipelines. Our work is particularly unique due to the breadth of resources we offer in one location.

16

Years MGI Employee Tenure

95%

% Repeat Partner Rate

65

Current Academic Institute Partners

56

Current Biopharma Partners

Why research-grade data matters in clinical trials

Why research-grade data matters in clinical trials

Clinical development relies on the integrity of underlying datasets. At every stage of a trial—whether early-phase safety studies or late-stage efficacy evaluations—decisions regarding a therapy’s trajectory depend on data that is accurate, reproducible, and interpretable. Research-grade standards are particularly critical when working with scarce or degraded patient material, where analytical precision determines whether samples can […]

Clinical OMICS: Where Multi-Omics Meets Clinical Reality

Multi-omic technologies have expanded rapidly over the past two decades. Researchers now have access to whole genome sequencing, spatial transcriptomics, proteomics, metabolomics, and more—all capable of capturing different aspects of disease biology. These tools have led to important discoveries, but they’ve also introduced new challenges: data fragmentation, inconsistent interpretation, and findings that fail to translate […]
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