Learn about some of the exciting news and events going on around the McDonnell Genome Institute.
Whole-Genome Sequencing Could Replace Cytogenetics in Assessing AML, Myelodysplastic Syndromes (Links to an external site)
Mar 11, 2021 | staff reporter NEW YORK — Whole-genome sequencing could serve as an alternative to cytogenetic analysis for acute myeloid leukemia or myelodysplastic syndromes, a new study has found.
Finnish Cardiometabolic Study Uncovers Strong Effect of Structural Variants (Links to an external site)
Mar 23, 2021 | staff reporter NEW YORK – Using genetic data for thousands of individuals from the Finnish population, an international team has tracked down more than a dozen loci linked to cardiometabolic traits, including two previously unappreciated structural variant (SV) sites that appear to have particularly strong ties to specific traits.
Mitochondrial Phenotypes Distinguish Pathogenic MFN2 Mutations by Pooled Functional Genomics Screen (Links to an external site)
Alex L Yenkin, John C Bramley, Jason E Waligorski, Colin L Kremitzki, Mariel J Liebeskind, Xinyuan E Xu, Maria A Vakaki, Vinay Chandrasekaran, Robi David Mitra, Jeffrey D Milbrandt, William J Buchser MGI identified subtle mitochondrial phenotypes & physically captured individual cells with single point mutations.
Whole genome sequencing shows promise in routine treatment of blood cancers, Washington U. study says (Links to an external site)
Michele Munz ST. LOUIS — Washington University researchers are among the first to show that whole genome sequencing, which used to be time-consuming and expensive, can be used routinely in patient care.
Promising role for whole genome sequencing in guiding blood cancer treatment (Links to an external site)
Sequencing results returned in a few days; costs similar to conventional testing by Julia Evangelou Strait•March 10, 2021