The McDonnell Genome Institute employs over 200 faculty and staff from a variety of disciplines.
Richard K. Wilson, Ph.D.
Director, Alan A. and Edith L. Wolff Distinguished Professor of Medicine
Elaine R. Mardis, Ph.D.
Co-Director, Robert E. and Louise F. Dunn Distinguished Professor of Medicine
Timothy Ley, M.D.
Associate Director, Professor of Medicine
Ira M. Hall, Ph.D.
Associate Director, Associate Professor of Medicine
Administrative Director, Data Production and Operations
The McDonnell Genome Institute is involved in a number of highly collaborative large-scale projects.
Reference Genomes Improvement
MGI's commitment to enhancing and diversifying human reference genomes.
Drug Gene Interaction Database (DGIdb)
Matching disease genes with potential drugs.
Genome Reference Consortium
Improving the human reference
Pediatric Cancer Genome Project
Decoding more than 600 childhood cancer genomes.
CIViC: Clinical Interpretations of Variants in Cancer
Discover supported clinical intepretations of mutations related to cancer and collaborate with colleagues to add variants and support for cancer-related mutations.
Research involving the McDonnell Genome Institute is published in some of the world's top journals.
The Genome Modeling Tools site provides reliable software for high-throughput genomic analysis that is easy to install and well documented. The software on the site is developed and maintained by the Informatics group at The McDonnell Genome Institute at Washington University School of Medicine.
TVAP focuses on the discovery and interpretation of genetic variants by providing a computational framework and data analysis tools for use with the latest DNA high-throughput sequencing technologies. TVAP is a component of the NHGRI's iSeqTools Network and is maintained by the Informatics group at MGI.
The Outreach Department reaches out to the St. Louis community by visiting local schools, giving talks and doing hands-on science with K-12 students. The department also conducts tours of the institute, invites groups to perform experiments in the facility's labs and provides internships for undergraduates from diverse backgrounds.