About The McDonnell Genome Institute

The McDonnell Genome Institute (MGI) is a world leader in the fast-paced, constantly changing field of genomics. A truly unique institution, we are pushing the limits of academic research by creating, testing, and implementing new approaches to the study of biology with the goal of understanding human health and disease, as well as evolution and the biology of other organisms.

As one of only three NIH funded large-scale sequencing centers in the United States, the McDonnell Genome Institute is helping to lead the way in high-speed, comprehensive genomics. Since its inception in 1993, the institute has played a vital role in the field of genome sequencing, receiving over $800 million in funding. The McDonnell Genome Institute began as a key player in the Human Genome Project – an international effort to decode all 6 billion letters of our genetic blueprint – ultimately contributing 25 percent of the finished sequence.

We work in concert with a number of other genome sequencing centers around the world.

More Information

Our Mission Statement

Our mission is to help improve the human condition by producing, studying, and interpreting high-quality genome-based data that drives biological discoveries that range from the bench to the hospital bedside. We value the open sharing of information and ideas and encourage collaboration while also engaging the next generation of scientists through educational outreach efforts.


Washington University School of Medicine
McDonnell Genome Institute
4444 Forest Park Ave
St. Louis, Missouri 63108


McDonnell Genome Institute
Washington University School of Medicine
Campus Box 8501
4444 Forest Park Ave
St. Louis, MO 63108

Phone: (314) 286-1800
Fax: (314) 286-1810

Email The McDonnell Genome Institute

Maps & Directions

By Public Transport
You can take the MetroLink to get to The McDonnell Genome Institute from Lambert Airport.

Get off the train at the Central West End station. Walk east (the same direction as the train you just got off of) to S Taylor Ave. Turn left at S Taylor Ave and walk one short block to Duncan Ave. Turn right on Duncan Ave and walk one block towards Newstead Ave. Before you get to Newstead, you will see a six-story black brick building on the left. The front entrance is on the Newstead side of the building. Take the elevator to the fifth floor and follow signs to the McDonnell Genome Institute main office. Call 314-286-1800 if you get lost.

By Car
From the airport, take I-70 east to I-170 south. Take I-170 south to I-64/40 east. Take I-64/40 east until you reach Kingshighway North. Take Kingshighway north (left onto Kingshighway) to Forest Park Ave. Go east on Forest Park Ave (right onto Forest Park). The institute will be 3 blocks from Kingshighway on your right.