Event presented by Genome Engineering and iPSC Center
January 21, 2021 8 AM to 1 PM
- 8 AM Charlie Gersbach, Ph.D., Rooney Family Associate Professor of Biomedical Engineering, Duke University
- Decoding and Programming the Genome with CRISPR Technologies
- 9 AM Ibrahim Kurt, Ph. D. Candidate, Harvard University
- CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells
- 9:30 AM Traver Hart, Assistant Professor, Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center
- CRISPR screening for functional genomics and cancer targeting
- 10 AM Shengdar Tsai, Assistant Member of the Department of Hematology, St. Jude Children’s Research Hospital
- Understanding genetic and epigenetic effects on CRISPR-Cas9 genome-wide activity with CHANGE-seq
- 10:30 AM Tim Peterson, Assistant Professor of Medicine, Washington University in St. Louis
- “Sphingolipids connect pathogens to aging-related disease”
- 11 AM John Doench, Director R&D, Institute Scientist, Broad Institute of MIT and Harvard University
- “Massively parallel variant-to-function mapping with CRISPR base editor screens”
- 11:30 AM Andrew Anzalone, Head of the Prime Editing Platform at Prime Medicine, Inc.
- “Prime Editing: Versatile and Precise Genome Editing without Double-strand Breaks or Donor DNA”
- 12 PM Panel Discussion:
- Including Monica Sentmanat, Ph.D./Assistant Director of GEiC, Steven Hoffman Illumina, Cell & Molecular Biology Segment Manager, and other speakers from the event
- “Off targeting using nucleases, base editors, prime editors, and in screens”
January 22, 2021 8 AM to 1 PM
- 8 AM Alejandro Chavez, Assistant Professor of Pathology & Cell Biology, Columbia University
- “Controlling gene expression with CRISPR-based tools”
- 8:30 AM Dongsheng Duan, Margaret Proctor Mulligan Professor in Medical Research, School of Medicine, University of Missouri, Columbia
- “CRISPR editing therapy for Duchenne muscular dystrophy”
- 9 AM Aron Geurts, Associate Professor, Department of Physiology, Medical College of Wisconsin
- Engineering Rats and Rat Model Resources
- 9:30 AM Xiaoxia Cui, Director of the Genome Engineering & iPSC Center, Washington University in St. Louis
- Reliable and Efficient Creation of Floxed Alleles in Mice
- 10 AM Andrew Yoo, Associate Professor of Developmental Biology, Washington University in St. Louis
- “Modeling late-onset neurodegenerative disorders via direct neuronal reprogramming of patient fibroblasts”
- 10:30 AM Martin Kampmann, Associate Professor, Institute for Neurodegenerative Diseases, UCSF Weill Institute for Neurosciences, University of California, San Francisco
- “CRISPR-based functional genomics in iPSC-derived models of brain disease”
- 11 AM. Luke Gilbert, Assistant Professor, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco
- “Genome-wide Programmable Transcriptional Memory by CRISPR-based Epigenome Editing”
- 11:30 AM Michael Kosicki, Postdoctoral Fellow, Lawrence Berkeley National Laboratory
- “Large deletions, small trouble”
- 12 PM Panel Discussion:
- Including Yi-Hsien Chen, Ph.D./Assistant Director of GEiC, Steven Hoffman Illumina, Cell & Molecular Biology Segment Manager, and other speakers from the event
- “On target large deletion, repression as KO alternative, off-targeting potential, continue first days”
Also, check out the online poster session to see all the great work being conducted.